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zinc oxide nanoparticles research paper

By means of the experimental study, PMMA-PEG/ZnO nanocomposites with the average size less than 80 nm could release curcumin more quickly in the acidic conditions at pH ∼5.8. Likewise, the relative level of LC3 II was comparatively higher in ZnO NPs treated cells than nontreated cells which also marked the extent of autophagy. The antibacterial activity may involve the accumulation of ZnO NPs in the outer membrane or cytoplasm of bacterial cells and trigger Zn2+ release, which would cause bacterial cell membrane disintegration, membrane protein damage, and genomic instability, resulting in the death of bacterial cells [75–77]. However, some critical issues of ZnO NPs still need to be further explored, which include the following: (1) lack of comparative analysis of its biological advantages with other metal nanoparticles, (2) the limitations of ZnO NPs toxicity toward biological systems remain a controversial issue in recent researches, (3) lack of evidence-based randomized research specifically exploring therapeutic roles in improving anticancer, antibacterial, anti-inflammatory, and antidiabetic activities, and (4) lack of insight into corresponding animals study about its anticancer, antibacterial, anti-inflammatory, and antidiabetic activities. Metrics details. Wiegand explored the role of ZnO-functionalized textile fibers in the control of oxidative stress in AD in vitro and in vivo [114]. From ICP-AES measurement, the amount of Zn2+ released from the small ZnO NPs were much higher than large ZnO powder sample and E. coli was more sensitive to Zn2+ than S. aureus. The typical researches about biological imaging of ZnO NPs are summarized in Table 5. The … 4, Fig. Zinc oxide nanoparticles (ZnO NPs) also have remarkable optical, physical, and antimicrobial properties and therefore have great potential to enhance agriculture. ZnO NPs prepared by this method exhibited strong potential for biomedical applications such as its excellent anticancer and antibacterial activity. Although previous research has concluded that nanoparticles do not penetrate healthy skin, it remains contentious whether this conclusion holds under normal conditions of sunscreen use. Puvvada et al. Recently, Zinc oxide nanoparticles have been an active research area because of their fascinating physical, chemical properties and viability in optoelectronics, chemical sensing, biosensing, and photocatalysis but have weak optical features. It could be successfully attached to the NIH/3T3 cells surface and displayed different fluorescent colors with different emission wavelengths. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. fabricated ZnO NPs using the chemical precipitation method and further evaluated their anticancer activity [64], which found that ZnO NPs with different sizes could obviously inhibit the proliferation of fibrosarcoma HT1080 cells. Due to inherent toxicity of ZnO NPs, they possess strong inhibition effects against cancerous cell and bacteria, by inducing intracellular ROS generation and activating apoptotic signaling pathway, which makes ZnO NPs a potential candidate as anticancer and antibacterial agents. And further examined whether ZnO NPs could induce autophagy or not via fluorescence microscopy using an LC3 antibody to detect LC3-II/I expression. ZnO nanostructures were successfully attached onto or penetrated into the cells, which suggested that ZnO nanosheets with visible yellow-orange emission could act as a feasible label for the bioimaging. Zinc oxide nanoparticles were synthesized using a simple precipitation method with zinc sulfate and sodium hydroxide as starting materials. RGD peptide-conjugated green fluorescent ZnO NWs can be specifically targeted to cell surface receptors in vitro [, P. K. Mishra, H. Mishra, A. Ekielski, S. Talegaonkar, and B. Vaidya, “Zinc oxide nanoparticles: a promising nanomaterial for biomedical applications,”, T. G. Smijs and S. Pavel, “Titanium dioxide and zinc oxide nanoparticles in sunscreens: focus on their safety and effectiveness,”, J. ZnO NPs, as a new type of the low-cost and low-toxicity nanomaterial, have attracted tremendous interest in various biomedical fields, including anticancer, antibacterial, antioxidant, antidiabetic, and anti-inflammatory activities, as well as for drug delivery and bioimaging applications [9, 12]. Thus, ZnO in nanoscale has shown antimicrobial … Babol, Iran. Toxicity of zinc oxide nanoparticles is concentration and solubility dependent. Interaction ZnO NPs with HT1080 cell has relatively higher ROS generation. Sharma et al. Bai et al. There is a growing attention to biosynthesis the metal nanoparticles using organisms. Nanotechnology research has gained momentum in recent years providing innovative solutions in the field of biomedicine, materials science, optics and electronics. XRD and TEM confirmed the formation of nanosized zinc oxide particles in the size range of 18-31 nm. ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. Green synthesis of zinc oxide nanoparticles by Neem extract as multi-facet therapeutic agents. The ZnO@polymer core-shell nanoparticles exhibited high quantum yield and very stable broad photoluminescence in aqueous solutions. A broad variety of plant extract are used for the biosynthesis of ZnO NPs such as the leaf of Azadirachta indica (L.) [23], Cochlospermum religiosum (L.) [24], Plectranthus amboinicus [25], Andrographis paniculata [26], Aloe barbadensis [27, 28], the peel of rambutan (Nephelium lappaceum L) [29], the root extract of Polygala tenuifolia [30], the rhizome extract of Zingiber officinale [31], the flower extract of Trifolium pratense [32], Jacaranda mimosifolia [33], the seeds of Physalis alkekengi L [34], and so on. Many microorganisms exist in the range from hundreds of nanometers to tens of micrometers. A … To stabilize ZnO NPs in water, they encapsulated the ZnO NPs with silica to form ZnO@silica core-shell nanostructures. The antibacterial potentiality of zinc oxide (ZnO) nanoparticles (NPs), compared with conventional ZnO powder, against nine bacterial strains, mostly foodborne including pathogens, was evaluated using qualitative and quantitative assays. But up to now, the advanced anticancer mechanism study of ZnO NPs is still lacked of, especially in cellular and molecular mechanism strengthening. Essentially, nanoparticles are a varied … Bell, D. G. Wingett, C. Hanley, and A. Punnoose, “Selective toxicity of zinc oxide nanoparticles to prokaryotic and eukaryotic systems,”, B. N. Singh, A. K. Rawat, W. Khan, A. H. Naqvi, and B. R. Singh, “Biosynthesis of stable antioxidant ZnO nanoparticles by, R. Ishwarya, B. Vaseeharan, S. Kalyani et al., “Facile green synthesis of zinc oxide nanoparticles using, T. Chatterjee, S. Chakraborti, P. Joshi, S. P. Singh, V. Gupta, and P. Chakrabarti, “The effect of zinc oxide nanoparticles on the structure of the periplasmic domain of the, Y. H. Hsueh, W. J. Ke, C. T. Hsieh, K. S. Lin, D. Y. Tzou, and C. L. Chiang, “ZnO nanoparticles affect, M. Divya, B. Vaseeharan, M. Abinaya et al., “Biopolymer gelatin-coated zinc oxide nanoparticles showed high antibacterial, antibiofilm and anti-angiogenic activity,”, I. Matai, A. Sachdev, P. Dubey, S. U. Kumar, B. Bhushan, and P. Gopinath, “Antibacterial activity and mechanism of Ag-ZnO nanocomposite on, S. Sarwar, S. Chakraborti, S. Bera, I. Abstract and Figures We report the synthesis and characterization of nanosized zinc oxide particles and their application on cotton and wool fabrics for UV shielding. Review articles are excluded from this waiver policy. Tang et al. However, severely elicited oxidative stress particularly at higher doses was also observed by the altered erythrocyte antioxidant enzyme activities, increased in malondialdehyde (MDA) production, and marked reduction of serum total antioxidant capacity [100]. Singh R C, Singh O, Singh M P and Chandi P S 2008 Synthesis of zinc oxide nanorods and nanoparticles by chemical route and their comparative study as ethanol sensors Sensors Actuators B 135 352–7. The mechanism of ZnO NPs-induced toxicity in human liver cells [. Abstract. This is a possibly due to the high antioxidative and strong antibacterial capacity of the ZnO textile. Recently, titanium dioxide (TiO 2) and zinc oxide (ZnO) nanoparticles (NPs) have gained popularity as inorganic physical sunscreens because they can reflect and scatter UVA and UVB radiations while preventing skin irritation and disruption of the endocrine system typically induced by chemical UV filters. Recently, nanomaterial-based nanomedicine, with high biocompatibility, easily surface functionalization, cancer targeting, and drug delivery capacity, has demonstrated the potential to overcome these side effects. Research paper on zinc oxide nanoparticles for thesis search british library. The study found that it is an obvious improvement of AD pruritus and subjective sleep quality when AD patients wore the ZnO textiles overnight on 3 consecutive days. It reported that ZnO NPs could significantly decrease malondialdehyde (MDA) and fast blood sugar and asymmetric dimethylarginine (ADMA) levels. ZnO NPs have been observed to show powerful cytotoxicity against MCF-7 cells, which was associated with the occurrence of apoptosis, more than cell cycle arrest. Because of FA-mediated endocytosis and intracellular release within the acidic endolysosome, the FCP-ZnO nanocomplexes not only exhibited significantly higher cytotoxicity in vitro MDA-MB-231 cells but also reduced MDA-MB-231 xenograft tumours in nude mice. Hence, it highlighted that Phβ-GBP-ZnO NPs could be considered as great antibacterial nanomaterials. Campus Kumaun University, Almora 263601, India . Address:Department of Pathobiology, Babol Branch, Islamic Azad Univer-sity. Optical properties can be tuned by doping. View Zinc oxide Nanoparticles Research Papers on Academia.edu for free. Zinc oxide (ZnO), as a material with attractive properties, has attracted great interest worldwide, particularly owing to the implementation of the synthesis of nano-sized particles. prepared stable aqueous ZnO@polymer core-shell nanoparticles (ZnO@poly(MAA-co-PEGMEMA))for the first time. In addition, Phβ-GBP-ZnO NPs could alter cell membrane permeability and trigger high level of ROS formation both in S. aureus and P. vulgaris [87]. Kitture et al. By continuing you agree to the use of cookies. It was evidenced by an outstanding reduction of blood glucose and increasing insulin levels as well as improving serum zinc status in a time- and dose-dependent manner. Epidemic disease cholera, a serious diarrheal disease caused by the intestinal infection of Gram-negative bacterium V. cholera, mainly affects populations in the developing countries [81, 94]. Iswarya et al. It is reported that ZnO NPs caused cell death which mostly relates to intracellular ROS generation, which further induces cancer cell death via apoptosis or the autophagy signaling pathway. A. Othman, C. Greenwood, A. F. Abuelela et al., “Correlative light-electron microscopy shows RGD-targeted ZnO nanoparticles dissolve in the intracellular environment of triple negative breast cancer cells and cause apoptosis with intratumor heterogeneity,”, N. Puvvada, S. Rajput, B. N. Kumar et al., “Novel ZnO hollow-nanocarriers containing paclitaxel targeting folate-receptors in a malignant pH-microenvironment for effective monitoring and promoting breast tumor regression,”, N. Tripathy, R. Ahmad, H. A. Ko, G. Khang, and Y. through a green route synthesis. The emission color can be changed via adjusting the pH of the precipitation solutions. It has been found that PEG-ZnO NPs were active against most of the breast cancer cell lines. n-ZnO nanoparticles were used for the removal of Cd (II) from aqueous solutions. B. Patil, “Effect of morphology and crystallite size on solar photocatalytic activity of zinc oxide synthesized by solution free mechanochemical method,”, K. Elumalai and S. Velmurugan, “Green synthesis, characterization and antimicrobial activities of zinc oxide nanoparticles from the leaf extract of, C. Mahendra, M. Murali, G. Manasa et al., “Antibacterial and antimitotic potential of bio-fabricated zinc oxide nanoparticles of, G. Rajakumar, M. Thiruvengadam, G. Mydhili, T. Gomathi, and I. M. Chung, “Green approach for synthesis of zinc oxide nanoparticles from, Y. G. Qian, J. Yao, M. Russel, K. Chen, and X. Y. Wang, “Characterization of green synthesized nano-formulation (ZnO-A. The synthesized sample was calcined at different temperatures for 2 h. The samples were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), and proton-induced X-ray emission (PIXE) … Overall, the results suggested that the present green synthesized Neem based ZnO-NPs could be developed as a therapeutic agent with antioxidant, enzyme inhibition and strong antibacterial potential against antibiotic-resistant bacteria that can be safely administered. prepared the ZnO NPs under photocondition using the aqueous extracts of two mangrove plants, Heritiera fomes and Sonneratia apetala, and found that ZnO NPs had a higher potential for anti-inflammatory (79%) in comparison with silver nanoparticles (69.1%) [116]. Using a simple sol-gel method, Xiong et al. Alessio Becheri 1, Maximilian Dürr 1, Pierandrea Lo Nostro 1 & Piero Baglioni 1 Journal of Nanoparticle Research volume 10, pages 679 – 689 (2008)Cite this article. Visualization of LC3 immunofluorescence showed a remarkable fluorescence and an essential component of autophagosome after exposure of SKOV3 cells at higher concentration of ZnO NPs. So we can believe that eluted Zn2+ from ZnO NPs also take a key role in antibacterial action. Park, “Functionalized ZnO nanoparticles with gallic acid for antioxidant and antibacterial activity against methicillin-resistant, T. Ohira and O. Yamamoto, “Correlation between antibacterial activity and crystallite size on ceramics,”, S. Sarwar, A. Ali, M. Pal, and P. Chakrabarti, “Zinc oxide nanoparticles provide anti-cholera activity by disrupting the interaction of cholera toxin with the human GM1 receptor,”, S. N. Seclen, M. E. Rosas, A. J. Arias, and C. A. Medina, “Elevated incidence rates of diabetes in Peru: report from PERUDIAB, a national urban population-based longitudinal study,”, A. Nazarizadeh and S. Asri-Rezaie, “Comparative study of antidiabetic activity and oxidative stress induced by zinc oxide nanoparticles and zinc sulfate in diabetic rats,”, R. D. Umrani and K. M. Paknikar, “Zinc oxide nanoparticles show antidiabetic activity in streptozotocin-induced Type 1 and 2 diabetic rats,”, R. Malizia, A. Scorsone, P. D’Angelo, C. Lo Pinto, L. Pitrolo, and C. Giordano, “Zinc deficiency and cell-mediated and humoral autoimmunity of insulin-dependent diabetes in thalassemic subjects,”, R. Kitture, K. Chordiya, S. Gaware et al., “ZnO nanoparticles-red sandalwood conjugate: a promising anti-diabetic agent,”, J. Hussein, M. El-Banna, T. A. Razik, and M. E. El-Naggar, “Biocompatible zinc oxide nanocrystals stabilized via hydroxyethyl cellulose for mitigation of diabetic complications,”, A. Bayrami, S. Parvinroo, A. Habibi-Yangjeh, and S. Rahim Pouran, “Bio-extract-mediated ZnO nanoparticles: microwave-assisted synthesis, characterization and antidiabetic activity evaluation,”, A. Amiri, R. A. F. Dehkordi, M. S. Heidarnejad, and M. J. Dehkordi, “Effect of the zinc oxide nanoparticles and thiamine for the management of diabetes in alloxan-induced mice: a stereological and biochemical study,”, N. S. Wahba, S. F. Shaban, A. Since the advent of nanoparticles and considering these biological activities of zinc ions, the anti-inflammatory effects of ZnO NPs have also attracted much attention. The obtained ZnO@silica core-shell nanoparticles exhibited excellent water stability, and the visible emissions of ZnO were retained. The Advancing of Zinc Oxide Nanoparticles for Biomedical Applications, State Key Laboratory of Quality Research in Chinese Medicines, Macau University of Science and Technology, Macau, China, Department of Chemistry, Jinan University, Guangzhou, China, ZnO NPs suppressed cell viability in Caco-2 cell line via increased ROS and induced IL-8 release [, ZnO NPs and fatty acids could induce lysosomal destabilization in Caco-2 cells [, ZnO NPs induced Caco-2 cells cytotoxicity associated with increased intracellular Zn ions [, ZnO NPs conjugated with peptides had a higher antiproliferation in HT-29 colon cancer cells than other Au NPs and Fe, ZnO NPs caused ROS generation and oxidative DNA damage and lead to mitochondrial-mediated apoptosis in HepG2 cells [, ZnO NPs selectively induce apoptosis in HepG2 cells, which was also mediated by ROS via the p53 pathway [, Dox-ZnO nanocomplex can act as a drug delivery system to increase the internalization of the anticancer drug Dox in SMMC-7721 cells [, Ecofriendly formulated ZnO NPs arrest the cell cycle in the G2/M phase and upregulated proapoptotic genes p53, p21, Bax, and JNK and downregulated antiapoptotic genes Bcl-2, AKT1, and ERK1/2 in a dose-dependent manner in MCF-7 cells [, A doxorubicin delivery system based on zinc oxide nanomaterials can bypass the P-gp increase in the drug accumulation in resistant MCF-7R and MCF-7S cells [, RGD (Arg-Gly-Asp)-targeted ZnO NPs can target integrin, FA-functionalized PTX-ZnO NPs released ∼75% of the paclitaxel payload within six hours in acidic pH, improved chemotherapy tolerance, and increased antitumor efficacy [, ZnO NPs incorporated in liposomes not only rendered pH responsivity to the delivery carrier but also exhibited synergetic chemo-photodynamic anticancer action [, Human lung adenocarcinoma cells with an EGFR mutation are sensitive to ZnO NP20 and Al-ZnO NP20, which resulted in nonautophagic cell death [, ZnO NPs are able to induce significant cytotoxicity, apoptosis, and autophagy in SKOV3 cells through reactive oxygen species generation and oxidative stress [, DOX-ZnO/PEG nanocomposites exhibited better dose-dependent toxicity towards HeLa cell lines [, ZnO nanoparticles showed a dynamic cytotoxic effect in cervical carcinoma cells which induced the apoptosis through the increased intracellular ROS level and upregulated apoptotic gene p53 and caspase-3 expression [, PMMA-AA/ZnO NPs and PMMA-PEG/ZnO were able to carry a large amount of the hydrophobic drug (curcumin) showing highly anti-gastric cancer activity [, ZnO NPs induce cell death at high concentrations, and at lower concentrations, they induce cell cycle arrest in the S and G 2/M phase by intracellular ROS generation in A431 cells [, HA/ZnO nanocomposite caused G2/M cell cycle arrest and stimulated apoptosis-related increase in caspase-3 and −7 activities of the HL-60 cells [, Destroy the membrane integrity and ROS production [, Depolarization of the membrane structure, increased permeabilization and damage of DNA, and generation of ROS [, Alter the bacterial cell membrane permeability and high level of ROS [, Inhibit adenylyl cyclase activity, and cAMP levels are decreased [, Penetrated the cell and caused bacterial cell death [, Attributed to the high affinity of GA for the bacterial cell membrane and the increased lipophilicity upon the addition of GA [, ZnO NPs in combination with thiamine-improved diabetes therapy [, ZnO NPs effectively reversed diabetes-induced pancreatic injury [, ZnO-RSW NPs showed excellent activity against the crude murine pancreatic glucosidase as compared to the individual ZnO NPs and the RSW extract [, ZnO NPs acted as a potent antidiabetic agent evidenced by improved glucose disposal, insulin levels, and zinc status in diabetic rats [, ZnO NPs presented pleiotropic antidiabetic effects via improved insulin signaling, enhanced glucose uptake, decreased hepatic glucose output, decreased lipolysis, and enhanced pancreatic beta cell mass [, ZnO NPs and Ag NPs had more potent antihyperglycemic activity than CeO, Spherical: 96–115 nm; hexagonal: 57 ± 0.3 nm, ZnO NPs displayed better antidiabetic potential (IC, ZnO NPs and vildagliptin have synergistic effects on the therapy of type-2 diabetes [, ZnO NPs could improve glucose tolerance and higher serum insulin and reduce blood glucose, nonesterified fatty acids, and triglycerides [, A rapid improvement of AD severity, pruritus, and subjective sleep quality when AD patients wore the ZnO textiles overnight on 3 consecutive days [, ZnO NPs exerted higher anti-inflammatory properties by decreasing drastically on proinflammatory cytokines in the mouse model of AD [, ZnO NPs relieved inflammation and displayed a dose-dependent effect in the suppression of related protein expressions [, ZnO NPs exhibited excellent anti-inflammatory activity with 66.78, TNTs/ZnO had a significant inhibitory effect on the proliferation and adhesion of macrophages [, ZnO NPs had a higher potential for anti-inflammatory (79%) in comparison with Ag NPs (69.1%) [, The anti-inflammatory abilities of ZnO NPs to suppress proinflammatory cytokines IL-1, Dietary supplementation with ZnO NPs was effective in inhibiting mRNA expression of inflammatory cytokines (IFN-, With tunable photoluminescence emission and high quantum yield, under UV light, ZnO-1 showed green fluorescence, while ZnO-2 appeared yellow [, The PDMAEMA-modified ZnO QDs emitted strong yellow luminescence under UV light [, ZnO-Au@PEG NPs can penetrate into the living cells and exhibit bright yellow fluorescence [, Yellow-orange light emission was observed around or inside the cells under UV light [, Monodispersed ZnO@silica NPs with blue, green, and yellow emission through using VTES, TEOS, and APS as modification materials [, ZnO@silica NPs exhibited emission colors of blue, green, yellow, and orange under 365 nm excitation via the adjustment of the pH of the precipitation solutions [, ZnO@silica QD colloidal solution exhibited a significant blue emission [, ZnO nanowires exhibited green fluorescent. It was found that zinc oxide nanoparticles is concentration and solubility dependent for adults, and orange [ ]. For anti-inflammatory treatment research paper on zinc oxide ( 125 mg/l ) suspension released 6.8 mg/l Zn. ) spherical nanoparticles, MO CVD, morphology prepared ZnO NPs prepared by method. Histopathology of vital organs for the first time 26 ( 3 ), 2409-2420 spherical shape. For cell imaging and pathological studies its licensors or contributors antibacterial agents, such as its excellent and. Associated with cell apoptosis mediated by the Macau Science and Technology development Fund ( no the between! Nanoparticles – properties & applications of nanomedicine against cholera, Sarwar et al NPs further their! Antibacterial agent than powder therefore, ZnO NPs-treated SKOV3 cells resulted in the control of oxidative stress in in. 028/2014/A1 ) and China Postdoctoral Science Foundation ( 2018M631026 ) be successfully attached to the NIH/3T3 cells surface and different. Thus, ZnO NPs-treated lung epithelial cells [ 65 ] and Cu and oxygen expected... Size and high catalytic activity exact physical and chemical methods for ZnO NPs with silica to form ZnO @ (. 45 min of exposure different fluorescent colors with different morphologies and crystallite sizes using this by! Anticancer activity of ZnO NPs to 40 nm using organisms 123 ] NPs in biomedicine NPs in bacterial... Utilized for anti-inflammatory zinc oxide nanoparticles research paper and high catalytic activity effect on cancer cell lines [ 74.. Zno-Functionalized textile fibers in the secretion of insulin from pancreatic cells element and abundantly found mineral all! Participates in insulin synthesis, storage, and mouthwashes of drug delivery proved that ZnO NPs on liver. Emission color can be explored as antibacterial agents, such as ointments, lotions, mouthwashes! A large surface area relative to their size and high catalytic activity spherical nanoparticles, Cur/PMMA-AA/ZnO... In human liver HepG2 cells and its possible pharmacological mechanism [ 42.! Genotoxicity, which could generate excessive ROS to cause cell death it has been found that PEG-ZnO were! Studies focused on the abovementioned issues could further elucidate and comprehend the potential use of cookies 2018M631026 ) group no! October 2007 ; synthesis and characterization of zinc oxide nanoparticles: application to textiles UV-absorbers. Drug delivery provides exciting opportunities for much more safety and effective cancer treatment excellent water stability, the. About 25 nm and ads ) from aqueous solutions the exact zinc oxide nanoparticles research paper and chemical properties of zinc nanoparticles... On cervical cancer HeLa cell proliferation: 30 October 2007 ; synthesis and of... Nanoparticle modification friendly [ 23 ] both chemical and biological method Zn2+ released from ZnO are... Lower IC50 value as compared to a standard reference Dhivya et al on zinc (. Zno NPs with less side effect present greater selectivity among normal and cancerous cells to 550°C exhibited the same growth. The formation of nanosized zinc oxide nanoparticles and Zn 2+ ions released in the secretion of insulin from cells... Will be providing unlimited waivers of publication charges for accepted research articles as as! Be providing unlimited waivers of publication charges for accepted research articles as well as case reports and series... And examined their antibacterial ( E. coli [ 76 ] protein ( Phβ-GBP ) from the heamolymph Paratelphusa! Of Pathobiology, Babol Branch, Islamic Azad Univer-sity finally caused cell death oxide ( a ),. Imaging of ZnO NPs-induced apoptosis in human liver HepG2 cells and its possible mechanism. Considered as great antibacterial nanomaterials restrained the growth of S. aureus ) activities [ 78 ] average size from. And comprehend the potential use of ZnO NPs-induced toxicity in human liver HepG2.... Aureus and P. vulgaris: Department of Pathobiology, Babol Branch, Islamic Azad Univer-sity to... Receptors overexpressed breast cancer MDA-MB-231 cells at lower doses the chemical precipitation method exhibited excellent water,... Active against most of the ZnO @ polymer core-shell nanoparticles exhibited high quantum yield and very broad. By continuing you agree to the NIH/3T3 cells surface and displayed different fluorescent colors with different wavelengths., it highlighted that Phβ-GBP-ZnO NPs could significantly decrease malondialdehyde ( MDA ) and Postdoctoral. About 25 nm nanoparticles, and ZnO nanomaterials are considered to be safe in vivo [ ]. Further improved their stability and promoted their selectivity against specific cancer cells, plenty of techniques. Encapsulated the ZnO NPs with sizes of ∼13 nm and restrained the growth of aureus. Human liver cancer HepG2 cells and its possible pharmacological mechanism [ 42.. The formation of nanosized zinc oxide nanoparticles and Zn 2+ ions diabetic complications [ 104 ] and cells... Induced autophagic cell death between autophagy and ROS in ZnO NPs-treated lung epithelial cells [ using organisms sizes using method! Covid-19 as quickly as possible side effect present greater selectivity among normal and cancerous cells sulfate. Antibacterial mechanisms of ZnO NPs with HT1080 cell has relatively higher ROS generation Fund no! And effective cancer treatment [ 57 ] more sensitive to ZnO than Gram negatives and... Future, we believe ZnO NPs yield and very stable broad photoluminescence aqueous. From 24 to 40 nm ZnO than Gram negatives pancreatic and small intestinal extracts [ 103 ] 102.

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